“World’s Largest Exercise Class” Gets Kids Active Around The Globe

In conjunction with May as Exercise is Medicine® Month, “The World’s Largest Exercise Class” is coming to children and schools around the world today.

Project ACES® (All Children Exercise Simultaneously) engages millions of children, parents and teachers each year to participate in physical activity at their schools and homes. Through Project ACES, children learn the value and importance of good nutrition, adequate physical fitness and healthy decision-making – lessons they can carry well into adulthood.

The 23rd-annual Project ACES Day will take place today, with most events occurring at 10 a.m. local time. Project ACES is the signature program of the nonprofit Youth Fitness Coalition (YFC), which is based in New Jersey. Project ACES clubs continue the momentum all year.

Schools can choose their activity, from walking to jogging, from martial arts to dancing. Students typically exercise for 15 to 45 minutes following an educational component. In the past, schools have incorporated celebrity guest speakers or used music in their Project ACES activities. The program has been recognized by multiple presidents, including Bill Clinton and Ronald Reagan, and has inspired events in 50 different countries. This chain of local events creates a global wave of exercise.

Project ACES Day coincides with Exercise is Medicine Month, a time for physicians, health-and-fitness professionals, supporting organizations and the public to recognize and celebrate the valuable health benefits of exercise. Founded by the American College of Sports Medicine (ACSM), Exercise is Medicine is a global program that encourages health care providers to assess patients’ physical activity levels at every visit.

Project ACES was created in 1989 by physical education teacher Len Saunders as a method of motivating children to exercise. It started with a massive letter-writing campaign to schools across the U.S., gathering 240,000 students to participate in the program the first year. Last year, Michigan alone had more than 500,000 participants.

“We’re addressing the need for novel physical education programs and promoting healthy lifestyle choices for students,” said YFC President H.J. Saunders. “We are proud of how far we’ve come, and we are honored to partner with ACSM and Exercise is Medicine. Project ACES activities can help combat the childhood obesity problem by making fitness personal and fun.”

Source:

American College of Sports Medicine Continue reading

Dendreon Initiates Phase 2 Trial Of PROVENGE In Patients With Localized Prostate Cancer Prior To Surgery

Dendreon Corporation
(Nasdaq: DNDN) announced that the Company has initiated a Phase 2
trial of PROVENGE(R) (sipuleucel-T), Dendreon’s investigational active
cellular immunotherapy for the treatment of prostate cancer, in men with
localized prostate cancer who are scheduled to undergo a radical
prostatectomy. The single-center trial called NeoACT (NEOadjuvant Active
Cellular immunoTherapy), or P07-1, which is being conducted at UCSF Helen
Diller Family Comprehensive Cancer Center, has begun enrolling
approximately 40 patients. NeoACT is the first of two new Phase 2 trials of
PROVENGE being initiated this year.

Each patient will receive a complete course of active treatment over a
one-month period beginning six to seven weeks prior to the patient’s
radical prostatectomy. The course of treatment will consist of three
infusions of PROVENGE-two weeks apart. Multiple safety and efficacy
endpoints will be evaluated including the immune response in the
prostatectomy specimens and in the peripheral blood. Following radical
prostatectomy, patients will be randomized to receive either a booster of
PROVENGE or no booster. Patients interested in additional information about
this trial may visit clinicaltrials and use the search term
“NeoACT.”

“I am pleased to help lead the NeoACT clinical trial, given the
therapeutic potential of immunotherapy for prostate cancer,” stated
Lawrence Fong, M.D., principal investigator of the NeoACT trial and
associate professor of medicine at UCSF Helen Diller Family Comprehensive
Cancer Center. “This study will provide a unique opportunity to examine the
immune response to PROVENGE in actual prostate cancer tissue and to examine
the correlation between immune responses in the tissue versus those in the
circulating blood.”

“Given the evidence of a survival benefit seen in our previous Phase 3
trial, D9901, in patients with advanced prostate cancer, we believe
PROVENGE may also have applicability to men with earlier stages of the
disease. This trial will help us better understand the mechanism of action
and biology of PROVENGE, as well as evaluate the potential of PROVENGE in
patients at high-risk for recurrence of their cancer following radical
prostatectomy,” stated Mark Frohlich, M.D., senior vice president, clinical
affairs and chief medical officer of Dendreon. “We are highly focused on
taking the steps necessary to get PROVENGE through the FDA approval process
in order to get this important immunotherapy to prostate cancer patients
with advanced disease who do not have any other reasonable options. We are
on track to complete the interim analysis of our ongoing Phase 3 IMPACT
trial during the latter half of this year.”

About Prostate Cancer

Prostate cancer is the most common non-skin cancer in the United States
and the third most common cancer worldwide. More than one million men in
the United States have prostate cancer, with an estimated 186,320 new cases
expected to be diagnosed in 2008, and approximately 28,660 men expected to
die this year from the disease. Currently there are limited treatment
options for men with advanced, metastatic prostate cancer.

About Active Cellular Immunotherapy with PROVENGE

PROVENGE may represent the first product in a new class of active
cellular immunotherapies (ACIs) that are uniquely designed to use live
human cells to engage the patient’s own immune system with the goal of
eliciting a specific long-lasting response against cancer. Active cellular
immunotherapy holds promise because it may provide patients with a
meaningful clinical benefit, such as survival, combined with low toxicity.

About Dendreon

Dendreon Corporation is a biotechnology company whose mission is to
target cancer and transform lives through the discovery, development and
commercialization of novel therapeutics. The Company applies its expertise
in antigen identification, engineering and cell processing to produce
active cellular immunotherapy product candidates designed to stimulate an
immune response. Dendreon is also developing an orally-available small
molecule called Trp-p8 that could be applicable to multiple types of cancer
as well as benign prostatic hyperplasia. The Company has its headquarters
in Seattle, Washington and is traded on the Nasdaq Global Market under the
symbol DNDN. For more information about the Company and its programs, visit
dendreon.

About UCSF

UCSF is a leading university dedicated to promoting health worldwide
through advanced biomedical research, graduate-level education in the life
sciences and health professions, and excellence in patient care. For more
information, please see ucsf.edu.

Except for historical information contained herein, this news release
contains forward-looking statements that are subject to risks and
uncertainties surrounding the efficacy of PROVENGE to treat men suffering
from prostate cancer, risks and uncertainties surrounding the presentation
of data to the FDA and approval of product applications by the FDA and
risks and uncertainties inherent in the process of discovering, developing
and commercializing drugs that are safe and effective for use as human
therapeutics. Factors that may cause such differences include risks related
to our limited operating history, risks associated with completing our
clinical trials, the risk that the safety and/or efficacy results of
existing clinical trials or from additional clinical trials for PROVENGE
will not support approval for a biologics license, the risk that the FDA
may interpret data differently than we do or require more data or a more
rigorous analysis of data than expected, the risk that the FDA will not
approve a product for which a biologics license has been applied, the risk
that the results of a clinical trial for PROVENGE or other product may not
be indicative of results obtained in a later clinical trial, risks that we
may lack the financial resources and access to capital to fund required
clinical trials or commercialization of PROVENGE, our dependence on the
efforts of third parties, and our dependence on intellectual property.
Further information on the factors and risks that could affect Dendreon’s
business, financial condition and results of operations are contained in
Dendreon’s public disclosure filings with the U.S. Securities and Exchange
Commission, which are available at sec.

Dendreon Corporation
dendreon

View drug information on Provenge. Continue reading

Inside The Infant Mind, New Study Shows That Babies Can Perform Sophisticated Analyses Of How The Physical World Should Behave

Over the past two decades, scientists have shown that
babies only a few months old have a solid grasp on basic rules of the
physical world. They understand that objects can’t wink in and out of
existence, and that objects can’t “teleport” from one spot to another.

Now, an international team of researchers co-led by MIT’s Josh Tenenbaum
has found that infants can use that knowledge to form surprisingly
sophisticated expectations of how novel situations will unfold.

Furthermore, the scientists developed a computational model of infant
cognition that accurately predicts infants’ surprise at events that
violate their conception of the physical world.

The model, which simulates a type of intelligence known as pure reasoning,
calculates the probability of a particular event, given what it knows
about how objects behave. The close correlation between the model’s
predictions and the infants’ actual responses to such events suggests that
infants reason in a similar way, says Tenenbaum, associate professor of
cognitive science and computation at MIT.

“Real intelligence is about finding yourself in situations that you’ve
never been in before but that have some abstract principles in common with
your experience, and using that abstract knowledge to reason productively
in the new situation,” he says.

The study, which appears in the May 27 issue of Science, is the first step
in a long-term effort to “reverse-engineer” infant cognition by studying
babies at ages 3-, 6- and 12-months (and other key stages through the
first two years of life) to map out what they know about the physical and
social world. That “3-6-12″ project is part of a larger Intelligence
Initiative at MIT, launched this year with the goal of understanding the
nature of intelligence and replicating it in machines.

Tenenbaum and Luca Bonatti of the Universitat Pompeu Fabra in Barcelona
are co-senior authors of the Science paper; the co-lead authors are Erno
Teglas of Central European University in Hungary and Edward Vul, a former
MIT student who worked with Tenenbaum and is now at the University of
California at San Diego.

Elizabeth Spelke, a professor of psychology at Harvard University, did
much of the pioneering work showing that babies understand abstract
principles about the physical world. Spelke also demonstrated that infants’
level of surprise can be measured by how long they look at something: The
more unexpected the event, the longer they watch.

Tenenbaum and Vul developed a computational model, known as an
“ideal-observer model,” to predict how long infants would look at animated
scenarios that were more or less consistent with their knowledge of
objects’ behavior. The model starts with abstract principles of how
objects can behave in general (the same principles that Spelke showed
infants have), then runs multiple simulations of how objects could behave
in a given situation.

In one example, 12-month-olds were shown four objects – three blue, one
red – bouncing around a container. After some time, the scene would be
covered, and during that time, one of the objects would exit the container
through an opening.

If the scene was blocked very briefly (0.04 seconds), infants would be
surprised if one of the objects farthest from the exit had left the
container. If the scene was obscured longer (2 seconds), the distance from
exit became less important and they were surprised only if the rare (red)
object exited first. At intermediate times, both distance to the exit and
number of objects mattered.

The computational model accurately predicted how long babies would look at
the same exit event under a dozen different scenarios, varying number of
objects, spatial position and time delay. This marks the first time that
infant cognition has been modeled with such quantitative precision, and
suggests that infants reason by mentally simulating possible scenarios and
figuring out which outcome is most likely, based on a few physical
principles.

“We don’t yet have a unified theory of how cognition works, but we’re
starting to make progress on describing core aspects of cognition that
previously were only described intuitively. Now we’re describing them
mathematically,” Tenenbaum says.

In addition to performing similar studies with younger infants, Tenenbaum
plans to further refine his model by adding other physical principles that
babies appear to understand, such as gravity or friction. “We think
infants are much smarter, in a sense, than this model is,” he says. “We
now need to do more experiments and model a broader range of the existing
literature to test exactly what they know.”

He is also developing similar models for infants’ “intuitive psychology,”
or understanding of how other people act. Such models of normal infant
cognition could help researchers figure out what goes wrong in disorders
such as autism. “We have to understand more precisely what the normal case
is like in order to understand how it breaks,” Tenenbaum says.

The research was funded by the Ministerio de Ciencia E Innovaci??n (Spain),
the James S. McDonnell Foundation, the Office of Naval Research, the Army
Research Office, and the Marie Curie Disorders and Coherence of the
Embodied Self Research Training Network.

Anne Trafton
MIT News Office Continue reading

Aerobic Exercise Safe And Effective For Rheumatoid Arthritis Patients

Cardio-Respiratory Aerobic Conditioning Improves Function; Lessens Joint Pain

Researchers from the University of Grenoble Medical School in France determined that cardio-respiratory aerobic exercise is safe for patients with stable rheumatoid arthritis (RA). The team found that RA patients who exercised regularly had improved function, less joint pain, and greater quality of life. Full findings of the study are now available online and will publish in the July print issue of Arthritis Care & Research, a journal of the American College of Rheumatology.

RA, a chronic inflammatory disease characterized by swollen joints, pain, stiffness, fatigue, and general malaise affects up to 1% of the global population, according to the World Health Organization (WHO). The Centers for Disease Control and Prevention (CDC) citing health-related quality of life (HRQL) studies found that RA patients were 40% more likely to report fair or poor general health and twice as likely to have a health-related activity limitation compared with those without arthritis.

The current study led by Athan Baillet, M.D., conducted an abstract search of relative medical journals for studies that researched RA patients and impact of aerobic exercise. The team analyzed 14 studies and meta-analysis included 510 patients in the intervention group and 530 in the control group. Participants in these studies had a mean age of 44-68 years and their RA disease duration was 1-16 years. Researchers compared HRQL, the Health Assessment Questionnaire (HAQ), joint count, and pain using a visual analog scale (VAS) among patients in the studies.

“Our results show that patients with stable RA would benefit from regular aerobic exercise,” said Dr. Baillet. “Cardio-respiratory conditioning appears safe and its effects, while small, help to reduce joint pain and improve function.” Researchers assessed the efficacy of exercise on RA symptoms using standardized mean differences (SMDs) which is the difference (between groups) of mean outcome variation from baseline/SD at baseline of aerobic exercises versus non-aerobic rehabilitation. Meta analysis of the research showed that exercise improved the post-intervention quality of life (SMD=0.39), HAQ score (SMD=0.24), and pain VAS (SMD=0.31). The difference in scores between those who exercised and those who had not are considered clinically meaningful by both patients and doctors noted the researchers.

The American College of Rheumatology states that exercise is beneficially for everyone, including those with RA, and currently recommends 150 minutes of moderate intensity aerobic activity each week. Safe forms of aerobic exercise, such as walking, aerobic dance, and aquatic exercise, help arthritis patients to control weight, and improve sleep, mood, and overall health.

“While past studies have indicated that RA patients are quite physically inactive, our study shows aerobic exercise to be a safe and beneficial intervention for this group. Further trials are needed to clearly determine the clinical impact of cardio-respiratory conditioning in the management of RA,” concluded Dr. Baillet.

Source: Wiley – Blackwell Continue reading

Fines For Off-Label Marketing Often Smaller Than Drug Company Profits From Practice

Some drug industry critics contend that “when drug makers are forced to pay huge fines” for promoting prescription drugs for off-label uses, “the amounts are small, compared with the money that can be made by promoting” those drugs, the AP/Hartford Courant reports. Physicians are permitted to prescribe drugs for uses that are not approved by FDA, but drug makers are prohibited by law from marketing drugs for off-label uses.

Since 1997, when the Justice Department began receiving funding earmarked to combat health care fraud, federal prosecutors have targeted drug companies for illegal marketing activities. In the past decade, the government has collected $11.87 billion in fines for violations and used the money to fund Medicare, Medicaid and other health programs.

One of the largest settlements occurred in 2004, when Pfizer paid $430 million to settle allegations that it marketed its epilepsy drug Neurontin for pain and psychiatric illnesses. Sales of the medication totaled $2.7 billion one year before the fines were issued. David Franklin, a medical liaison who became a whistleblower against the company, said that even after the settlement, doctors told him that other pharmaceutical companies were continuing to promote their drugs for off-label uses. “The $430 million penalty was widely referred to as a slap on the wrist,” he said (Lavoie, AP/Hartford Courant, 5/10).

“Reprinted with permission from kaisernetwork. You can view the entire Kaiser Daily Health Policy Report, search the archives, or sign up for email delivery at kaisernetwork/dailyreports/healthpolicy. The Kaiser Daily Health Policy Report is published for kaisernetwork, a free service of The Henry J. Kaiser Family Foundation . © 2005 Advisory Board Company and Kaiser Family Foundation. All rights reserved.

View drug information on Neurontin. Continue reading

New Adaptive Structures Inspired By Plants That Can Move

The Mimosa plant, which folds its leaves when they’re touched, is inspiring a new class of adaptive structures designed to twist, bend, stiffen and even heal themselves. University of Michigan researchers are leading their development.

Mechanical engineering professor Kon-Well Wang presented the team’s latest work at the American Association for the Advancement of Science’s 2011 Annual Meeting in Washington D.C. He also spoke at a news briefing earlier that day. Wang is the Stephan P. Timoshenko Collegiate Professor of Mechanical Engineering and chair of the Department of Mechanical Engineering.

“This is quite different from other traditional adaptive materials approaches,” Wang said. “In general, people use solid-state materials to make adaptive structures. This is really a unique concept inspired by biology.”

Researchers at U-M and Penn State University are studying how plants like the Mimosa can change shape, and they’re working to replicate the mechanisms in artificial cells. Today, their artificial cells are palm-size and larger. But they’re trying to shrink them by building them with microstructures and nanofibers. They’re also exploring how to replicate the mechanisms by which plants heal themselves.

“We want to put it all together to create hyper-cellular structures with circulatory networks,” Wang said.

The Mimosa is among the plant varieties that exhibit specialized “nastic motions,” large movements you can see in real time with the naked eye, said Erik Nielsen, assistant professor in the U-M Department of Molecular, Cellular and Developmental Biology.

The phenomenon is made possible by osmosis, the flow of water in and out of plants’ cells. Triggers such as touch cause water to leave certain plant cells, collapsing them. Water enters other cells, expanding them. These microscopic shifts allow the plants to move and change shape on a larger scale.

It’s hydraulics, the researchers say.

“We know that plants can deform with large actuation through this pumping action,” Wang said. “This and several other characteristics of plant cells and cell walls have inspired us to initiate ideas that could concurrently realize many of the features that we want to achieve for adaptive structures.”

Nielsen believes nastic movements might be a good place to start trying to replicate plant motions because they don’t require new growth or a reorganization of cells.

“These rapid, nastic motions are based on cells and tissues that are already there,” Nielsen said. “It’s easy for a plant to build new cells and tissues during growth, but it’s not as easy to engineer an object or machine to completely change the way it’s organized. We hope studying these motions can inform us about how to make efficient adaptive materials that display some of the same types of flexibility that we see in biological systems.”

When this technology matures, Wang said it could enable robots that change shape like elephant trunks or snakes to maneuver under a bridge or through a tunnel, but then turn rigid to grab a hold of something. It also could lead to morphing wings that would allow airplanes to behave more like birds, changing their wing shape and stiffness in response to their environment or the task at hand.

Notes:

At U-M, Michael Mayer, associate professor in the departments of Biomedical Engineering and Chemical Engineering, is also involved in the research. At Penn State, the project involves Charles Bakis, distinguished professor of engineering sciences and mechanics, and Christopher Rahn, professor of mechanical engineering. This project is currently funded by the National Science Foundation.

Source:
Nicole Casal Moore
University of Michigan Continue reading

Holiday Celebrations Can Cause More Than A Hangover

Some people end up with more than a headache following a holiday party. For more than 12 million Americans, ingredients in both food and beverages can trigger allergy and asthma symptoms, according to the American Academy of Allergy, Asthma & Immunology (AAAAI). These reactions can range from a mild rash or stomachache to swelling of the throat or difficulty breathing.

While a food intolerance occurs when the digestive system is unable to properly breakdown the food, an allergic reaction to a food involves the immune system.

“There is a big difference between food intolerance and food allergy, and that difference can have serious consequences,” according to S. Allan Bock, MD, FAAAAI, Vice Chair of the AAAAI’s Adverse Reactions to Foods Committee. “Consuming a food you are intolerant to can make you feel miserable for a while. However, if you are allergic to an ingredient, your body’s reaction could be life threatening. During the holidays, it is very important that individuals who have been diagnosed with a food allergy not let their guard down when eating out and at parties.”

The growing confusion between intolerance and allergy can be avoided through proper testing and diagnosis by an allergist/immunologist. An allergist/immunologist will take a complete and detailed history, decide what testing is indicated and then determine a course of action and if needed, create an emergency action plan.

To locate an allergist, visit the AAAAI Physician Referral Directory here.

Signs of a food allergy include:

– A rash, or red, itchy skin (hives/urticaria)

– Stuffy or itchy nose, sneezing, or itchy and teary eyes

– Vomiting, stomach cramps or diarrhea

– Angioedema or swelling

– Difficulty breathing including throat closing, hacking cough (mimics choking at times), wheezing

Some people with food allergies can have a serious reaction called anaphylaxis. Signs of this kind of reaction include: difficulty breathing, dizziness or loss of consciousness. If you have any of these symptoms, particularly after eating, seek medical care immediately (call 911). Don’t wait to see if your symptoms go away or get better on their own.

“It is crucial that food allergic individuals carry their emergency self-injectable epinephrine. Almost all fatalities have occurred in people who accidentally ingested an allergen and had no way to treat it immediately. It’s also important to recognize that having asthma is an additional risk factor for a life-threatening event,” cautioned Bock.

Source:

American Academy of Allergy, Asthma & Immunology (AAAAI) Continue reading

MSU Researcher Helps Develop Computer Game For Ugandan Children Recovering From Cerebral Malaria

The computer program Captain’s Log — originally used with individuals diagnosed with attention deficit hyperactivity disorder, brain injuries or learning disabilities — is being adapted to rehabilitate Ugandan children who are survivors of cerebral malaria.

Michael Boivin, a Michigan State University associate professor of neurology and ophthalmology and of psychiatry, and Bruno Giordani, a University of Michigan associate professor of psychiatry, are leading the project.

“So far as we know, this will be the first attempt to implement a cognitive rehabilitation training program in Uganda with children in the aftermath of brain injury,” Boivin said. “Such programs for children with special needs are readily available in America, and in other parts of the developed world, but not in Africa.”

Every 30 seconds a child in Africa dies from malaria — around 1 million every year, he said. Cerebral malaria is a severe form of malaria that affects the brain and is fatal in about 15 percent to 30 percent of the cases for hospitalized children.

“Our most recent follow-up evaluation of our cerebral malaria children indicates that 26 percent of them have persisting mild to moderate cognitive impairment, mostly in the area of attention and to some extent in visual-spatial working memory,” Boivin said.

The computer game is a comprehensive set of computerized cognitive training programs consisting of five modules including developmental, visual motor skills, conceptual skills, numeric concepts with memory skills and attention skills.

The research team is hoping that this intervention can help cerebral malaria-affected school-age Ugandan children improve their cognitive skills, leading to improvements for both activities of daily living and school-related learning and skill development.

“The program attempts to do so with the use of 33 multilevel brain-training exercises designed to help develop and remediate attention, concentration, memory, eye-hand coordination, basic numeric concepts, problem solving-reasoning skills, self-esteem and self-control,” Boivin said.

Originally developed in 1985, the program is used with children 6 years and older and adults and has been used in a variety of therapeutic, school and home settings in all 50 states, U.S. territories and 23 foreign countries. Also, the program has been adapted for use in a wide range of non-English speaking settings.

Boivin and Giordani have trained a Ugandan study team to help implement and evaluate the program.

“We trained our study team at Mulago Hospital in Uganda, and they helped us in testing the program,” Boivin said. “The onsite project research manager, Paul Bangirana, can now program and set up Captain’s Log on his own.”

###

This pilot study is supported by a Global Health Research and Training grant from U-M and through Boivin’s startup faculty funding.

In addition, the study will provide an opportunity to establish partnerships between the U-M Neuropsychology Section; MSU International Neurologic and Psychiatric Epidemiology Program; and the Department of Pediatrics and Child Health, Makerere University School of Medicine, Uganda.

Michigan State University has been advancing knowledge and transforming lives through innovative teaching, research and outreach for more than 150 years. MSU is known internationally as a major public university with global reach and extraordinary impact. Its 17 degree-granting colleges attract scholars worldwide who are interested in combining education with practical problem solving.

Source: Michael J. Boivin

Michigan State University Continue reading

Tendency To Obesity Starts With Pre-Schoolers

When it comes to understanding where tendencies to overweight and obesity develop, you have to begin with the very young, says John Spence, a behavioural scientist in the Faculty of Physical Education and Recreation at the University of Alberta.

His research, the first of its kind to look at North American kids and published in the International Journal of Pediatric Obesity, examined four- and five year olds’ avoidance or approach behaviours to food and their relationship with body weight.

What he’s found may help to unlock the causes of obesity and what we can do to prevent a condition in Canada where, alarmingly, 26 per cent of 2 to 17 year olds are overweight or obese.

Spence and his team recruited 1730 Canadian children into the study – an equal mix of boys and girls, and four and five year-olds – via immunization clinics from 2005 to 2007 when they came for their pre-school vaccinations. Kids were classified according to body weight status and parents asked to complete the UK-developed Children’s Eating Behaviour Questionnaire (CEBQ), which has been used in European studies to establish the relationship between food behaviours and body weight in children.

Parents were given a list of statements relating to how their child responded to food, for example, “My child loves food,” or “My child eats more when worried” and asked if or to what extent the behaviour occurred.

The results of the two-year study were in line with what Spence had anticipated. He found significant differences between the children in different weight status groups for food responsiveness, emotional over-eating, enjoyment of food, satiety responsiveness, slowness in eating, and food fussiness.

“It does appear that children, not surprisingly, who are demonstrating approach behaviours to food (eating when upset, or eating when bored, for example) are going to be more overweight whereas children who are demonstrating avoidance behaviours (such as fussy or slow eating) are more likely to be underweight. But the issue now is: how do children develop these approach or avoidance tendencies to food?” says Spence.

“This model suggests that to some extent this is influenced by the household environment where the parents may be rewarding children for certain types of behaviours. It would suggest that there is some dynamic in the household that is leading children to be more approach or avoidant in relation to food.”

Spence says the results, which show clear linear relationships across the body weight groups, bode well for his follow-up research, now in progress.

“If we are seeing associations between where children live and play; if there are associations between the environment and the weight status of the child then we have to try and figure out how that environment influences that child,” says Spence.

“Is it exposure to food, prevention or promotion of physical activity? Is it the way they interact with their food as shaped by their environment? This is more of a household variable than one would expect, so is the child being rewarded or punished in relation to their food and is that then related to their weight status? Is there education we can be providing to parents?

“These have potential intervention implications because if we can identify this and understand what the causes of approach and avoidance behaviours are, we can identify what we can intervene on.”

Spence has begun a longitudinal study following the children from the original study who are now seven and eight year-olds. This time researchers will probe deeper and with confidence knowing their work is grounded in a solid foundation of findings consistent with European studies that have used the CBEQ to establish these associations between food behaviours and body weight.

“Now we’ll be situating (our research) in a larger framework with more variables and we’ll be looking to see how some of these work together,” says Spence. “We’ll look to see if, in children who are more approach-oriented to food, we are seeing more food being consumed and are they consuming some of the ‘bad’ food.”

Spence says he expects governments to step in with policies once researchers know more. “Now that we’ve established the associations, we need to know how to change things, and if we change things how do we implement those in policy, and affect populations.”

Source:
Jane Hurly
University of Alberta – Faculty of Physical Education and Recreation Continue reading